Table 2. Structures used for comparison in this study, with PDB code, species, sequence identity and r.m.s.d. when superposed onto hCof1.
| PDB code | Protein | Species | Sequence identity (%) | R.m.s.d. () | Method |
|---|---|---|---|---|---|
| 4bex | hCof1 | H. sapiens | X-ray | ||
| 1q8x | Cofilin 1 | H. sapiens | 99 | 1.73 | NMR |
| 1ak6 | Destrin | H. sapiens | 65 | 1.83 | NMR |
| 1tvj | Cofilin | G. gallus | 77 | 1.51 | NMR |
| 1cof | Cofilin | S. cerevisiae | 28 | 1.11 | X-ray |
| 2i2q | Cofilin | S. pombe | 31 | 1.02 | X-ray |
| 1f7s | ADF | A. thaliana | 29 | 1.15 | X-ray |
| 2l72 | ADF | T. gondii | 12 | 1.99 | NMR |
| 2lj8 | Cofilin | T. brucei | 19 | 1.92 | NMR |
| 2kvk | Actin-severing and dynamics regulator | L. donovani | 17 | 1.53 | NMR |
| 3q2b | Cofilin 1 homologue | P. falciparum | 19 | 1.40 | X-ray |