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. Author manuscript; available in PMC: 2015 Jun 9.
Published in final edited form as: DNA Repair (Amst). 2013 Dec 4;13:10–21. doi: 10.1016/j.dnarep.2013.10.011

Fig. 8.

Fig. 8

DNA damage signaling in mMYH-overproducing HCT15 cells after H2O2 treatment. Cells transfected with pcDNA or mMYH were treated with 25 μM H2O2 for 1 hr, and then recovered for different time intervals as indicated. Cell extracts were subjected to Western blotting analysis. P-Chk1 and P-Cdc25C are Ser 317-phosphorylated Chk1 and Ser 216-phosphorylated Cdc25C, respectively.