Table 4.
Association of the development of AEs with 24-week OS rates
| AE (n) | 24-week OS rate, % | 95% CI | P valuea |
|---|---|---|---|
| Anemia | |||
| Present (362) | 84 | 79–88 | 0.733 |
| Absent (1308) | 84 | 82–86 | |
| Hand–foot syndrome | |||
| Present (607) | 94 | 92–96 | <0.001 |
| Absent (1063) | 77 | 73–80 | |
| Hypertension | |||
| Present (774) | 87 | 84–89 | <0.001 |
| Absent (337) | 76 | 70–81 | |
| Hypothyroidism | |||
| Present (653) | 87 | 84–90 | 0.003 |
| Absent (1017) | 82 | 79–85 | |
| Leukopenia | |||
| Present (747) | 91 | 88–93 | <0.001 |
| Absent (923) | 78 | 74–81 | |
| Thrombocytopenia | |||
| Present (1165) | 87 | 85–89 | <0.001 |
| Absent (505) | 76 | 71–80 | |
OS, overall survival.
aLog-rank test.