Table 4. Association between waist—to—height ratio and platelet indices among 17327 participants.
| Variable | Waist-to-height ratio (OR, 95% CI) | P–trend | |||||
|---|---|---|---|---|---|---|---|
| <0.50 | 0.50– | 0.55– | ≥0.60 | ||||
| MPV (low/normal) | Total | Univariate model | 1.00 | 1.06 (0.95, 1.19) | 1.24 (1.09, 1.41) | 1.38 (1.17, 1.64) | <0.001 |
| Multivariate model a | 1.00 | 1.06 (0.95, 1.18) | 1.26 (1.10, 1.43) | 1.42 (1.19, 1.70) | <0.001 | ||
| Male | Univariate model | 1.00 | 1.04 (0.89, 1.22) | 1.40 (1.16, 1.68) | 1.17 (0.86, 1.58) | 0.004 | |
| Multivariate model b | 1.00 | 1.04 (0.89, 1.22) | 1.37 (1.14, 1.66) | 1.12 (0.82, 1.52) | 0.011 | ||
| Female | Univariate model | 1.00 | 1.08 (0.92, 1.25) | 1.13 (0.95, 1.36) | 1.54 (1.25, 1.90) | <0.001 | |
| Multivariate model b | 1.00 | 1.11 (0.95, 1.29) | 1.21 (1.00, 1.46) | 1.68 (1.34, 2.09) | <0.001 | ||
| MPV (high/normal) | Total | Univariate model | 1.00 | 1.02 (0.91, 1.15) | 0.91 (0.78, 1.06) | 0.75 (0.60, 0.94) | 0.022 |
| Multivariate model a | 1.00 | 1.02 (0.90, 1.15) | 0.89 (0.76, 1.04) | 0.72 (0.57, 0.91) | <0.001 | ||
| Male | Univariate model | 1.00 | 1.06 (0.88, 1.27) | 0.93 (0.73, 1.20) | 0.86 (0.58, 1.28) | 0.495 | |
| Multivariate model b | 1.00 | 1.06 (0.88, 1.27) | 0.95 (0.74, 1.22) | 0.86 (0.58, 1.30) | 0.557 | ||
| Female | Univariate model | 1.00 | 1.00 (0.86, 1.18) | 0.88 (0.73, 1.07) | 0.68 (0.51, 0.90) | 0.011 | |
| Multivariate model b | 1.00 | 0.98 (0.84, 1.15) | 0.84 (0.69, 1.03) | 0.65 (0.48, 0.87) | 0.004 | ||
| PDW (low/normal) | Total | Univariate model | 1.00 | 1.20 (1.09, 1.32) | 1.48 (1.33, 1.65) | 2.32 (2.01, 2.68) | <0.001 |
| Multivariate model a | 1.00 | 1.22 (1.11, 1.34) | 1.53 (1.36, 1.71) | 2.46 (2.12, 2.85) | <0.001 | ||
| Male | Univariate model | 1.00 | 1.15 (1.00, 1.33) | 1.32 (1.12, 1.56) | 1.86 (1.45, 2.39) | <0.001 | |
| Multivariate model b | 1.00 | 1.17 (1.01, 1.35) | 1.37 (1.15, 1.62) | 1.97 (1.52, 2.54) | <0.001 | ||
| Female | Univariate model | 1.00 | 1.23 (1.09, 1.40) | 1.61 (1.39, 1.86) | 2.60 (2.18, 3.10) | <0.001 | |
| Multivariate model b | 1.00 | 1.27 (1.11, 1.44) | 1.69 (1.46, 1.97) | 2.82 (2.34, 3.39) | <0.001 | ||
| PDW (high/normal) | Total | Univariate model | 1.00 | 0.93 (0.86, 1.00) | 0.72 (0.66, 0.80) | 0.64 (0.55, 0.74) | <0.001 |
| Multivariate model a | 1.00 | 0.89 (0.83, 0.97) | 0.69 (0.62, 0.76) | 0.61 (0.52, 0.71) | <0.001 | ||
| Male | Univariate model | 1.00 | 0.93 (0.83, 1.04) | 0.62 (0.53, 0.72) | 0.59 (0.46, 0.76) | <0.001 | |
| Multivariate model b | 1.00 | 0.89 (0.79, 1.00) | 0.57 (0.49, 0.67) | 0.54 (0.42, 0.70) | <0.001 | ||
| Female | Univariate model | 1.00 | 0.91 (0.82, 1.01) | 0.82 (0.72, 0.94) | 0.69 (0.57, 0.84) | <0.001 | |
| Multivariate model b | 1.000 | 0.89 (0.80, 0.99) | 0.79 (0.68, 0.90) | 0.65 (0.54, 0.79) | <0.001 | ||
95%CI: 95% confidence interval; fl = femtolitre; MPV: mean platelet volume; PDW: platelet distribution width; OR: odds ratio.
Subjects were divided into three subgroups according to the reference ranges for Chinese adults: low (<15%), normal (15–17%) and high (>17%) for platelet distribution width, as well as low (<7 fl), normal (7–11 fl), high (>11 fl) for mean platelet volume, respectively.
The subjects were divided into four groups according to waist—to—height ratios: <0.50, 0.50–, 0.55—and ≥0.60.
aAdjusted for age (continuous), gender, smoking status, passive smoke exposure, drinking status, physical activity, doing housework, hyperlipemia and hypertension.
bAdjusted for age (continuous), smoking status, passive smoke exposure, drinking status, physical activity, doing housework, hyperlipemia and hypertension.