Table 1. Methylation of the host cells gene promoters in the study group (N = 171).
| Gene promoter | Number (%) of methylated samples in | ||||
|---|---|---|---|---|---|
| Normal cytology a | LSIL/CIN1 b | HSIL/CIN2 c | HSIL/CIN3 d | CC e | |
| CCNA1 | 5 (12.5) | 12 (30.0) | 9 (23.1) | 16 (38.1) | 8 (80.0) |
| CDH1 | 33 (82.5) | 30 (75.0) | 31 (79.5) | 32 (76.2) | 10 (100.0) |
| C13ORF18 | 3 (7.5) | 11 (27.5) | 10 (25.6) | 9 (21.4) | 9 (90.0) |
| DAPK1 | 22 (55.0) | 20 (50.0) | 18 (46.2) | 16 (38.1) | 6 (60.0) |
| HIC1 | 27 (67.5) | 30 (75.0) | 27 (69.2) | 24 (57.1) | 8 (80.0) |
| RARβ2 | 25 (62.5) | 14 (35.0) | 24 (61.5) | 26 (61.9) | 9 (90.0) |
| hTERT1 | 0 (0.0) | 5 (12.5) | 2 (5.1) | 3 (7.1) | 7 (70.0) |
| hTERT2 | 3 (7.5) | 5 (12.5) | 0 (0.0) | 1 (2.4) | 6 (60.0) |
| TWIST1 | 11 (27.5) | 0 (0.0) | 9 (23.1) | 9 (21.4) | 8 (80.0) |
aN = 40;
bN = 40;
cN = 39;
dN = 42;
eN = 10;
LSIL, low-grade squamous cell intraepithelial lesion; HSIL, high-grade squamous cell intraepithelial lesion; CIN, cervical intraepithelial neoplasia; CC, cervical cancer.