Fig 3. Severe islet endocrine cell and β-cell deficiency in pancreata of diabetic dogs.

Representative images for control (control #10)(a-f) and diabetic dogs (diabetic #15)(g-l). Total pancreas was detected with GFP autofluorescence (red). (a-c, g-i) synaptophysin (green), (d-f, j-l) insulin (green). (b, e, h, k) White boxes indicate areas of interest, shown at higher magnification on right (c, f, i, l). Scale bars: 2mm.