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. 2015 May 27;71(Pt 6):799–803. doi: 10.1107/S2053230X15008468

Table 2. Comparison of F-atom contacts and bridge torsion angles for inhibitor 26 .

hDHFR26 pcDHFR26
Trifluoro contacts ()
3FAsp21 carbonyl 3.5 3FIle65CG2 3.9
4FSer59carbonyl 3.4 4FPhe69CE 5.8
5FIle60CG 3.9 5FIle123CD1 6.9
Bridge conformation ()
C7C6N9C1 3.9 C7C6N9C1 33.2
C6N9C1C6 63.2 C6N9C1C6 45.9
C7C6N9CH3 167.0 C7C6N9CH3 152.0