. 2015 May 27;71(Pt 6):799–803. doi: 10.1107/S2053230X15008468

Table 3. Contacts () involving the inhibitor N9 CH₃ with Val115 (hDHFR) or Ile123 (pcDHFR), Thr56 (hDHFR) or Thr61 (pcDHFR), and Ile60 (hDHFR) or Ile65 (pcDHFR).

The shortest distances for each complex are given for comparison.

DHFR	N9 CH₃Val115/Ile123	N9 CH₃Thr56/Thr61	N9 CH₃Ile60/Ile65
hDHFR22	Carbonyl O, 5.3; CG1, 6.9	CG2, 4.6	CG1, 4.5
pcDHFR22 (F69N)	Carbonyl O, 4.7; CG1, 4.8	CG2, 3.8	CG1, 4.7
hDHFR26	Carbonyl O, 5.2; CG2, 5.8	CG2, 3.9	CG1, 4.5
pcDHFR26	Carbonyl O, 4.5; CG1, 5.4	CG2, 3.6	CG1, 5.2
pcDHFR24	Carbonyl O, 4.5; CD1, 4.3	CG2, 3.6	CG1, 4.2

Table 3. Contacts () involving the inhibitor N9 CH3 with Val115 (hDHFR) or Ile123 (pcDHFR), Thr56 (hDHFR) or Thr61 (pcDHFR), and Ile60 (hDHFR) or Ile65 (pcDHFR).