FIG. 5.

Effects of CPZ on conformational states of EnvA TM. (A) Receptor-bound virions were mixed with liposomes, the indicated amount of CPZ was added, and the mixtures were then incubated under step 1 conditions. (B) Samples were subjected to the two-step protocol in the presence (lanes 2 to 5) or absence (lane 1) of peptide R99 and in the presence (lanes 3 to 5) or absence (lanes 1 and 2) of the indicated concentration of CPZ. Samples were then processed as described in the legend to Fig. 1. Lanes 1 and 2 were not adjacent in the original gel. The values on the left or right are molecular sizes in kilodaltons.