FIGURE 6.

Effect of pitavastatin treatment on capillary tube formation in cultured MSCs. A, Representative photographs of MSCs cultured on Matrigel after incubation under normoxia (upper) or hypoxia (lower). Culture of MSCs was performed without serum (left), with serum (center), and with serum-free plus pitavastatin (1 µM, right) (n = 4 for each group). B, Quantitative analysis of tube formation. Data are mean ± SD (n = 4) for each group. ΨP < 0.05 versus normoxia (FBS⁻, pitava⁻), ∗P < 0.05 versus normoxia (FBS⁺, pitava⁻), ∬P < 0.05 versus hypoxia (FBS⁻, pitava⁻), †P < 0.05 versus hypoxia (FBS⁺, pitava⁻).