Table 2.
Night shift work (years) | Trend test | Ever worked night shift | ||||
---|---|---|---|---|---|---|
Never | 1 – 2 years | 3 – 9 years | 10+ years | P-value | HR (95% CI) | |
Cases/Person-years | 1,014/120,899 | 399/39,095 | 235/20,817 | 138/8,899 | 772/68,811 | |
Basic multivariatea | 1.00 (reference) | 1.17 (1.04,1.31) | 1.23 (1.06,1.41) | 1.42 (1.19,1.70) | <0.0001 | 1.22 (1.11,1.34) |
+ Lifestyle factorsb | 1.00 (reference) | 1.14 (1.01,1.28) | 1.18 (1.02,1.36) | 1.35 (1.13,1.62) | 0.0007 | 1.18 (1.08,1.30) |
+ Body mass index | 1.00 (reference) | 1.09 (0.97,1.22) | 1.11 (0.96,1.28) | 1.23 (1.03,1.47) | 0.022 | 1.12 (1.01,1.23) |
Basic covariates: age, questionnaire cycle, family history of diabetes, education, and neighborhood socioeconomic status
Lifestyle factors: vigorous activity levels, smoking, alcohol, energy intake, dietary pattern, and coffee, decaffeinated coffee, soda consumption, and diet soda consumption