FIG. 4.

Map of the murine IFN-α/β locus on chromosome 4. The map of the IFN cluster was reconstructed from the partial supercontig assembly of chromosome 4 of the NCBI (accession no. NT_039271.2). Arrows indicate the direction of transcription. As breaks still occur in the assembled sequence, the order and orientation of presented segments (separated by //) might still be found to vary. A fragment encompassing three limitin genes, IFN-α7/10, IFN-α-11, IFN-α8/6, IFN-α5, and IFN-α4 occurs twice in the NCBI assembly. This duplication likely represents an assembly artifact since the duplicated segment is not connected to any other in the assembled sequence and since no experimental data suggest such a duplication in any mouse strain.