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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: J Clin Pharmacol. 2015 Mar 30;55(7):798–808. doi: 10.1002/jcph.481

Table 1.

Data are number (%) or Mean (SD) for plasma and genital viral loads (VL). Rebound is detectable virus after achieving < 50 copies/mL.

Plasma Genital
ATV n=9 EFV n=11 P-value ATV n=9 EFV n=11 P-value
Baseline log10 VL 4.39 (1.02) 4.66 (0.95) 0.545 3.25 (1.27) 3.23 (0.86) 0.9
VL <50 copies/mL 5 (56%) 9 (82%) 0.336 8 (89%) 11 (100%) 0.5
Rebound 1 (20%) 1 (11%) 0.604 1 (20%) 1 (11%) 0.6
Days to VL < 50 109.6 (71.5) 77.1 (5.7) 0.394 23.3 (9.5) 25.8 (14.5) 0.9
Days to 50% decline in VL 8.2 (4.9) 9.3 (7.4) 0.707 7.3 (3.5) 9.3 (7.7) 0.5
Days to >1 log10 drop in VL 56.3 (119.1) 12.7 (10.1) 0.305 62.9 (136.0) 25.0 (43.4) 0.5
End of study log10 VL 1.98 (0.61) 2.79 (1.68) 0.129 1.93 (0.50) 2.54 (1.25) 0.1