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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Pharmacogenet Genomics. 2015 Jul;25(7):343–353. doi: 10.1097/FPC.0000000000000143

Figure 1. Linkage Disequilibrium (LD) in the CYP4F locus for all non-monomorphic SNPs in the participants from a) SCF and b) CANHR sample sets, by r2 measure.

Figure 1

Pairwise comparisons illustrate low LD between most SNPs. The rs2189784 and rs2108622 SNPs are found in tighter LD in the samples from CANHR participants than in the samples from SCF participants. These patterns illustrate the effects of potential founder effects and population isolation, resulting in differences in genetic patterns found in regional subgroups of Alaska. Variant pairs with LD scores closer to 100 were more often inherited together than not. Scores were calculated with Haploview version 4.2. Haplotype blocks determined by confidence intervals.