Table 1.
Direction | Ctrl | M4 | M10 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Anterograde | 06h | 24h | 48h |
00 00 |
06h | 24h | 48h |
00 00 |
06h | 24h | 48h |
Number vesicles | 13 | 18 | 16 | 3 | 26 | 17 | 4 | 28 | 35 | ||
In Motion (%) | 51 | 70 | 58 | 51 | 69 | 70 | 45 | 79 | 69 | ||
Max run length (μm) | 14.5±9.7 | 16.8±9.0 | 14.1±4.8 | 18.9±6.5 | 16.36±6.9 | 18.9±8.2# | 19.53±26 | 23.7±11## | 18.6±8.3# | ||
Average velocity (μ/sec) | 1±0.9 | 1.5±0.6 | 1.3±0.5 | 0.6±0.1 | 1.5±0.7 | 1.5±0.6 | 0.4±0.6 | 1.6±0.6*** | 1.4±0.5** | ||
Peak velocity (μ/sec) | 1.4±1.2 | 1.8±0.7 | 1.7±0.7 | 0.7±0.2 | 1.9±0.6 | 1.9±0.6 | 1.0±0.3 | 1.9±0.6 | 1.7±0.7 | ||
Retrograde | 06h | 24h | 48h | 06h | 24h | 48h | 06h | 24h | 48h | ||
Number vesicles | 60 | 27 | 38 | 46 | 26 | 26 | 66 | 21 | 23 | ||
In Motion (%) | 53 | 55 | 59 | 56 | 55 | 60 | 52 | 21 | 23 | ||
Max run length (μm) | 12.7±6.9 | 13.4±7.3 | 14.5±8.1 | 12.9±8.1 | 12.2±6.1 | 16.1±9.7 | 14.4±10.5 | 15.0±10 | 15.5±9.7 | ||
Average velocity (μ/sec) | 0.8±0.4 | 0.9±0.3 | 0.8±0.4 | 0.7±0.2 | 0.7±0.2 | 0.7±0.3 | 0.8±0.4 | 0.9±0.3 | 0.9±0.4 | ||
Peak velocity (μ/sec) | 1.2±0.8 | 1.3±0.4 | 1.1±0.4 | 1.1±0.5 | 1.0±0.3 | 1.0±0.4 | 1.1±0.6 | 1.2±0.3 | 1.2±0.6 | ||
| |||||||||||
Antero/Retro | 0.2 | 0.6 | 0.4 | 0.07 | 1 | 0.6 | 0.06 | 1.3 | 1.5 |
p<0.001 vs. 06h within the same condition;
p<0.01 vs. 06h within the same condition
p<0.01 vs. Ctrl within the same time point;
p<0.05 vs. Ctrl within the same time point