Figure 4. Absence of IL-17A attenuates EV features caused by VV inoculation in the OVA sensitized skin of ft/ft mice.
A–C. Gross appearance (A), area of primary lesions (B), and number of satellite lesions (C). Dashed circles indicate primary lesions. Arrows indicate satellite lesions. D. Viral load. E–H, H&E stained skin sections (200× magnification) (E), epidermal thickness (F), number of neutrophils (G), cytokine mRNA expression (H). Scale bars: 100 µm. The line in the box indicates median and the whiskers represent from the minimum to maximum (n = 5 per group). *P < .05 and **P < .01. ns, not significant. nd, not detectable.