Skip to main content
. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Bioorg Med Chem. 2015 Apr 9;23(13):3603–3617. doi: 10.1016/j.bmc.2015.04.006

Figure 12.

Figure 12

PDT efficacy of Compound 2 (PS2) and Photofrin (PFII) on human NSCLC xenograft tissue. Xenograft tissue was dissociated, plated onto collagen-1 matrix and cultured for 4 days. The tumor cells form clusters segregated from stromal cells. The cultures were treated for 4 hours with medium containing 6µg/ml PFII or 1µg/ml PS 2. The cell-associated PS fluorescence was recorded immediately after uptake and after a 24-hour chase period. The phase microscopic and corresponding fluorescent images at 100× are reproduced.