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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Bioorg Med Chem. 2015 Apr 9;23(13):3603–3617. doi: 10.1016/j.bmc.2015.04.006

Figure 9.

Figure 9

Correlation of compound uptake and photoreaction. Confluent epithelial cells were incubated for 4 hours with 800 nM (for fluorescent imaging in A) or 100 nM (for biochemical analysis in B–D) compounds listed at the top. After a 4-h chase period, the cell-associated fluorescence was determined by imaging. The cells in B–D were treated with 665nm light (3 J/cm2), extracted and the relative amount of oxidative crosslinking of STAT3 and level of EGFR and phospho- and total p38 MAPK were determined by immunoblotting.