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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Mol Carcinog. 2014 Dec 9;55(1):3–14. doi: 10.1002/mc.22253

Figure 5.

Figure 5

The effect of silibinin and DHS on ASZ tumor allograft growth in nude mice. ASZ cells were injected into nude mice and treated with vehicle (0.5% CMC), silibinin (200 mg/kg), or DHS (200 mg/kg) via oral gavage and analyzed for (A) tumor volume (twice weekly), (B) tumor weight (at the end of the study), and (C) mouse weight as detailed in ‘Materials and Methods.’ The data shows average tumor volume ± SEM, n = 7–10 mice per group. (D) Blood was collected from mice at various time points (0–180 min) after final treatment to illustrate drug oral bioavailability as detailed in ‘Materials and Methods.’ *P ≤ 0.05, significant with respect to vehicle control.