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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: J Biochem Mol Toxicol. 2014 Oct 30;29(3):129–134. doi: 10.1002/jbt.21676

FIGURE 2.

FIGURE 2

Downregulation Nav mRNA in SK-N-AS cells by deltamethrin is prevented by the Nav antagonist TTX and the intracellular calcium chelator BAPTA-AM. (A) Nav 1.2 mRNA relative expression in response to pretreatment of cells with the Nav antagonist TTX and depletion of intracellular calcium. (B) Nav 1.3 mRNA expression in response to pretreatment of cells with the Nav inhibitor TTX and depletion of intracellular calcium. Data represent 2ΔΔCt analysis of qPCR data, normalized to control. Significance determined by 2-way ANOVA with Student-Neuman Keul’s post hoc test. * = p < 0.05 compared to control; n = 3–4. Error bars represent ±SEM