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CBD attenuates DOX-induced proinflammatory response in the heart. Real-time PCR shows significant increase of (A) TNFA, (B) IL1B, (C) MCP-1 mRNA level. Pretreatment with CBD significantly attenuates DOX-induced increased proinflammatory chemokine levels. *P < 0.05 versus vehicle group; #P < 0.05 versus DOX group; n = 4–6/group.
