Table A1.

Distribution of Pathogenic and Likely Pathogenic Variants in Individuals Tested for Suspected CRCP Syndromes With NGS Panels at the University of Washington Molecular Genetics Laboratory, According to Type of Inheritance and Penetrance of Colorectal Cancer of Associated CRCP Syndrome

Variants by CRCP Syndrome Type	No. of Individuals
Lynch associated	30
Autosomal dominant CRCP with high colorectal cancer penetrance	13
Autosomal recessive CRCP with high colorectal cancer penetrance	4
Autosomal dominant CRCP with low colorectal cancer penetrance	7
No CRCP-associated variant identified	297

Abbreviations: CRCP, colorectal cancer and polyposis syndromes; NGS, next-generation sequencing.