Table IV.
Association of polymorphic variants of the SOD2 and BACH2 genes with the risk of diabetes.
Gene | rs number | Allelesa | Genotypes casesb | Genotypes controlsb | Ptrend value | Pgenotropic value | Pallelic value | ORdominant(95% CI)c; P-value | ORrecessive(95% CI)d; P-value |
---|---|---|---|---|---|---|---|---|---|
BACH2 | rs3757247 | A/G | 32/82/26 | 116/177/75 | 0.320 | 0.084 | 0.327 | 1.554 (0.989–2.441); 0.055 | 0.891 (0.543–1.463); 0.648 |
SOD2 | rs4880 | C/T | 32/72/37 | 98/185/86 | 0.330 | 0.613 | 0.332 | 1.232 (0.780–1.945); 0.371 | 1.171 (0.749–1.829); 0.488 |
Underline denotes the minor allele in the control samples
genotype order: DD/Dd/dd (d is the minor allele in the control samples)
dominant model: dd+Dd vs. DD (d is the minor allele)
recessive model: dd vs Dd+DD (d is the minor allele) CI, confidence interval; OR, odds ratio.