Table 2.

Proton magnetic resonance spectroscopic imaging voxel metabolite value and metabolite ratio (Mean +/- SD) of control subjects and patients with multiple sclerosis (NAWM vs. Control and WML vs. Control p > 0.05; * p < 0.05 vs. NAWM)

value	Control	NAWM	WM lesion
NAA	106.1 +/- 20.9	102.23 +/- 20.2	102.61 +/- 29.9
Cr	61.7 +/- 13.0	62.13 +/- 14.2	63.94 +/- 13.0
mI	36.67 +/- 4.9	39.32 +/- 10.9	39.39 +/- 8.3
Cho	53.6 +/- 17.0	54.77 +/- 16.5	51.06 +/- 13.1
NAA/Cr	1.73 +/- 0.24	1.67 +/- 0.18	1.6 +/- 0.22
Cho/Cr	0.86 +/- 0.11	0.89 +/- 0.19	0.80 +/- 0.15*
mI/Cr	0.61 +/- 0.11	0.63 +/- 0.10	0.62 +/- 0.12

NAA: N acetylaspartate; Cr: Creatine; mI: Myoinositol; Cho: choline; NAWM: normal appearing white matter; WML: white matter lesions