Table 4.
Comparison between MAF in our data set and the data set from Lu et al. 2013 [15] Nat Genetics
| SNP and MA | Data from the this study | Data from Lu et al. 2013 [15] | ||||||
|---|---|---|---|---|---|---|---|---|
| (108 cases/300 controls) | (652 cases/2,761 controls) | |||||||
| Lead SNP | Allele | MAF (cases) | MAF (controls) | OR | MAF (cases) | MAF (controls) | OR | p-value |
| rs7606754 | A | 0.34 | 0.37 | 0.9 | 0.37 | 0.33 | 1.2 | 6.0E-03 |
| rs4894535a | T | 0.16 | 0.12 | 1.4 | 0.21 | 0.16 | 1.5 | 1.3E-06 |
| rs1324183 | A | 0.25 | 0.28 | 0.9 | 0.24 | 0.2 | 1.3 | 8.8E-05 |
| rs1536482 | A | 0.45 | 0.41 | 1.1 | 0.4 | 0.34 | 1.3 | 1.2E-03 |
| rs7044529a | T | 0.14 | 0.13 | 1.1 | 0.18 | 0.14 | 1.3 | 3.0E-04 |
| rs11145951a | T | 0.44 | 0.49 | 0.82 | 0.45 | 0.49 | 0.89 | 0.03 |
| rs2721051a | T | 0.14 | 0.11 | 1.4 | 0.14 | 0.1 | 1.5 | 3.2E-06 |
| rs9938149 | C | 0.29 | 0.32 | 0.9 | 0.32 | 0.36 | 1.2 | 7.1E-03 |
SNP single nucleotide polymorphism; MA minor allele; MAF minor allele frequency; OR odds ratio
a These SNPs had similar trends of allele frequency changes between cases and controls as those reported by Lu et al. [15]