Table 7.

The antiviral activity of MBS extract on HSV-1 by the direct virucidal effect and the prophylactic effect on MRC-5 cell line

Protocol	Time	aCC50 mg/ml	b IC50 mg/ml	cSI
dDVI	0 h	136.58 ± 55.08	24.17 ± 1.43	5.69 ± 0.35
	1 h	136.58 ± 55.08	13.8 ± 0.44	9.91 ± 0.31
	2 h	136.58 ± 55.08	7.62 ± 0.71	18.23 ± 1.69
Acyclovir	2 h	0.35 ± 0.005	0.014 ± 0.0005	22.56 ± 1.11
eIVR	30 min	136.58 ± 55.08	15.53 ± 0.74	8.83 ± 0.42
	1 h	136.58 ± 55.08	12.72 ± 1.12	10.9 ± 0.96
Acyclovir	1 h	0.37 ± 0.005	0.02 ± 0.003	15.04 ± 1.9

Note: a cytotoxic concentration 50, b Inhibitory concentration 50, c selective index ^dDVI: the direct virus inactivation. ^eIVR: the inhibition in virus infection after specific cell treatment