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. 2015 Jun 10;5:11338. doi: 10.1038/srep11338

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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lncRNA functional network was constructed by the model of LNCSIM based on disease semantic similarity model 1, where each node represents one lncRNA and the links was connected if lncRNA pair has a functional similarity equal to or greater than the similarity cutoff (here the cutoff is 0.3 considering the fact that known lncRNA-disease associations is seriously incomplete currently). The size of a node is proportional to the degree of the node. The network is visualized by cytoscape (http://cytoscape.github.io/).