Table 7.
Therapeutic regimens used in cats affected by feline leishmaniosis
| Drug and dosage | Duration | Number of treated cats | References |
|---|---|---|---|
| Allopurinol (10–15 mg/kg/12 h, 20 mg/kg/24 h, 25 mg/cat/12 h, 100 mg/cat/24 h) PO | 6 months - 3 years | 15 | [14, 37, 50, 54–56, 64, 65] |
| Meglumine antimoniate (20–50 mg/kg/24 h SC) | 20–30 days | 1 | [59, 63] |
| Meglumine antimoniate (175 mg/cat/48 h IM) | 55 days | 1 | [51] |
| Meglumine antimoniate (5 mg/kg/24 h SC) in combination with Ketoconazole (10 mg/kg/24 h PO) | 3 cycles of 4 weeks, 10 days apart | 1 | [36] |
| Fluconazole (5 mg/kg/24 h PO) | 60 days | 1a | [37] |
| Spiramycin (150.000 IU/kg) and Metrodinazole (25 mg/kg) 24 h PO | 35 days | 1a | [37] |
| Itraconazole (50 mg/cat/24 h PO) | 60 days | 1a | [37] |
SC: subcutaneous; IM: intamuscular; PO: per os a a same cat was treated with the three different therapeutic regimens at subsequent times