Table 5.
Relationships of serum TARC or SCF with clinicopathological characteristics of GC in the validation dataset
| Clinicopathological characteristics | TARC | SCF | CEA |
|---|---|---|---|
| γs (P-value) | γs (P-value) | γs (P-value) | |
| Gender (Male:Female) | −0.097 (0.154) | −0.070 (0.305) | −0.079 (0.294) |
| Age (years)† | 0.073 (0.282) | 0.091 (0.184) | −0.031 (0.682) |
| H. pylori infection (−/+) | 0.095 (0.161) | 0.057 (0.397) | 0.009 (0.903) |
| Histology (Intestinal:Diffuse) | −0.051 (0.635) | −0.185 (0.082) | 0.090 (0.422) |
| Tumor location (Lower:Middle:Upper)‡ | −0.012 (0.908) | 0.001 (0.999) | 0.191 (0.087) |
| Tumor size (<3 cm; 3–5 cm and >5 cm)§ | 0.227 (0.028)* | 0.119 (0.255) | 0.417 (0.001)* |
| T-stage (T1a:T1b:T2:T3:T4)¶ | 0.340 (0.001)* | 0.166 (0.118) | 0.102 (0.274) |
| N-stage (N0:N1:N2:N3)¶ | 0.318 (0.002)* | 0.074 (0.485) | 0.078 (0.489) |
| Distant Metastasis (M0:M1)¶ | 0.346 (0.001)* | 0.137 (0.199) | 0.464 (0.001)* |
| Overall stage (I:II:III:IV)¶ | 0.279 (0.008)* | 0.156 (0.142) | 0.142 (0.058) |
These values are statistically significant.
This is a continuous variable. Therefore, the correlation is evaluated by Pearson's correlation (γp).
Tumor location is divided into three areas: lower third (antrum-angle), middle third (low body-middle body), and upper third (upper body-cardia).
Tumor size was classified into three groups: <3 cm, 3–5 cm, and >5 cm.
TNM stage was evaluated according to the 7th International Union Against Cancer-TNM stage. CEA, carcinoembryonic antigen; SCF, stem cell factor; TARC, thymus activation-regulated chemokine. γs, Spearman's correlation coefficient. P < 0.05 (two-tailed) was considered statistically significant.