Table 1.
Clinical features according to each biomarker expression
| All Patients n = 32 (%) | LMP1 |
CLA |
Cell Origin |
||||
|---|---|---|---|---|---|---|---|
| Positive n = 19 | Negative n = 10 | Positive n = 9 | Negative n = 22 | NK-cell type n = 27 | T-cell type n = 5 | ||
| Age at Diagnosis, n (%) | |||||||
| ≤60 | 25 (78) | 15 (79) | 8 (80) | 8 (89) | 16 (73) | 21 (78) | 4 (80) |
| >60 | 7 (22) | 4 (21) | 2 (20) | 1 (11) | 6 (27) | 6 (22) | 1 (20) |
| Sex, n (%) | |||||||
| Male | 19 (59) | 9 (47) | 3 (30) | 9 (100) | 10 (45) | 12 (44) | 1 (20) |
| Female | 13 (41) | 10 (53) | 7 (70) | 0 (0) | 12 (55) | 15 (56) | 4 (80) |
| PS, n (%) | |||||||
| 0 or 1 | 30 (94) | 17 (89) | 10 (100) | 9 (100) | 20 (91) | 25 (93) | 5 (100) |
| >1 | 2 (6) | 2 (11) | 0 (0) | 0 (0) | 2 (9) | 2 (7) | 0 (0) |
| Serum LDH Level, n (%) | |||||||
| ≤Normal | 25 (78) | 15 (79) | 7 (70) | 7 (78) | 17 (77) | 20 (74) | 5 (100) |
| >Normal | 7 (22) | 4 (21) | 3 (30) | 2 (22) | 5 (23) | 7 (26) | 0 (0) |
| B Symptoms, n (%) | |||||||
| Absent | 20 (63) | 13 (68) | 5 (50) | 4 (44) | 15 (68) | 16 (59) | 4 (80) |
| Present | 12 (37) | 6 (32) | 5 (50) | 5 (56) | 7 (32) | 11 (41) | 1 (20) |
| Stage, n (%) | |||||||
| IE | 22 (69) | 12 (63) | 8 (80) | 5 (56) | 16 (73) | 20 (74) | 2 (40) |
| IIE | 10 (31) | 7 (37) | 2 (20) | 4 (44) | 6 (27) | 7 (26) | 3 (60) |
| Skin Involvement, n (%) | |||||||
| Absent | 18 (56) | 14 (74) | 3 (30) | 4 (44) | 14 (64) | 13 (48) | 5 (100) |
| Present | 14 (44) | 5 (26) | 7 (70) | 5 (56) | 8 (36) | 14 (52) | 0 (0) |
| IPI, n (%) | |||||||
| 0 | 19 (59) | 11 (58) | 6 (60) | 6 (67) | 12 (55) | 15 (56) | 4 (80) |
| 1 | 10 (31) | 6 (32) | 3 (30) | 3 (33) | 7 (32) | 9 (33) | 1 (20) |
| 2 | 3 (9) | 2 (11) | 1 (10) | 0 (0) | 3 (14) | 3 (11) | 0 (0) |
| NK-PI, n (%) | |||||||
| 0 | 11 (34) | 7 (37) | 3 (30) | 1 (11) | 9 (41) | 9 (33) | 2 (40) |
| 1 | 9 (28) | 4 (21) | 4 (40) | 5 (56) | 4 (18) | 8 (30) | 1 (20) |
| 2 | 9 (28) | 7 (37) | 1 (10) | 2 (22) | 7 (32) | 7 (26) | 2 (40) |
| 3 | 3 (9) | 1 (5) | 2 (20) | 1 (11) | 2 (9) | 3 (11) | 0 (0) |
CLA, cutaneous lymphocyte antigen; IPI, international prognostic index; LDH, lactate dehydrogenase; LMP1, latent membrane protein 1; NK-PI, NK/T-cell lymphoma prognostic index; PS, performance status.