Table 1.
Patient characteristics of this study
| Characteristics | pNET | PC | CP | AIP | Normal | P-value |
|---|---|---|---|---|---|---|
| Number | 69 | 50 | 50 | 20 | 112 | |
| Sex (%) | ||||||
| Male | 39 (56.5) | 28 (56.0) | 30 (60.0) | 17 (85.0) | 67 (59.8) | 0.709 |
| Female | 30 (43.5) | 22 (44.0) | 20 (40.0) | 3 (15.0) | 45 (40.2) | |
| Age (years) | ||||||
| Mean ± SD Range | 57.5 ± 13.9 (20–85) | 63.8 ± 9.5 (46–84) | 53.0 ± 14.0 (25–75) | 63.6 ± 11.4 (35–75) | 56.5 ± 14.3 (26–99) | 0.286 |
| PPI use (%) | ||||||
| Yes | 19 (27.5) | 19 (38.0) | 28 (56.0) | 9 (45.0) | 0 (0) | <0.0001* |
| No | 50 (72.5) | 31 (62.0) | 22 (44.0) | 11 (55.0) | 112 (100) | |
| Tumor classification (%) | ||||||
| Non-functioning | 39 (56.5) | |||||
| Functioning | 30 (43.5) | |||||
| Gastrinoma | 17 (24.6) | |||||
| Insulinoma | 10 (14.5) | |||||
| Others† | 3 (4.3) | |||||
| Histological grade | ||||||
| G1 | 40 (58.0) | |||||
| G2 | 22 (31.9) | |||||
| G1 or G2‡ (an exact Ki67 not determined) | 7 (10.1) | |||||
| Tumor size (pancreas) (%) | ||||||
| <2 cm | 33 (47.8) | |||||
| >2 cm | 15 (21.7) | |||||
| Postoperative | 21 (30.5) | |||||
| Liver metastasis (%) | ||||||
| Yes | 28 (40.6) | |||||
| No | 41 (59.4) | |||||
| Presence of MEN-1 (%) | ||||||
| Yes | 6 (8.7) | |||||
| No | 63 (91.3) | |||||
P-value was calculated using 2 × 2 χ2-test or Student t-test or Fisher's exact test.
*
Significant difference using Fisher's exact test.
†
Others comprise of a glucagonoma, a somatostatinoma and a VIPoma.
‡
Cytology was performed but not determined Ki67 value and diagnosed with well-differentiated tumor which corresponds to NET G1 or G2 according to the WHO 2010 classification. AIP, autoimmune pancreatitis; CP, chronic pancreatitis; MEN-1, multiple endocrine neoplasia type 1; PC, pancreatic cancer; pNET, pancreatic neuroendocrine tumor; PPI, proton pump inhibitor.