Table 2.
p-PDH expression and clinicopathological features of colorectal cancer
| Phospho-PDH-E1α | Positive (n = 34) | Negative (n = 70) | P-value |
|---|---|---|---|
| Patient background | |||
| Gender (Male/Female) | 22/12 | 43/27 | 0.7461 |
| Age (mean ± SD) | 66.0 ± 10.4 | 63.5 ± 13.3 | 0.1669 |
| BMI (kg/m2) | 23.6 (20.6, 25.6) | 21.9 (20.3, 25.6) | 0.4316 |
| CEA (ng/mL) | 2.5 (1, 6) | 3 (2.0, 7.3) | 0.4401 |
| CA19-9 (U/mL) | 12.5 (5.0, 23.3) | 12.5 (7.0, 21.3) | 0.8538 |
| Tumor characteristics | |||
| Tumor diameter (mm) | 37 (22, 52) | 35 (22, 52) | 0.6126 |
| Location | |||
| C/A/T | 5/6/5 | 3/9/9 | 0.0883 |
| D/S/R | 3/3/12 | 1/17/31 | |
| Tumor type | |||
| Type 0 | 11 | 15 | 0.2275 |
| Type 1/2/3/4/5 | 1/16/4/0/2 | 5/38/12/0/0 | |
| Histological type | |||
| tub1/tub2/pap | 10/18/1 | 20/44/1 | 0.2893 |
| por/muc | 2/3 | 2/3 | |
| Depth | |||
| T0/T1/T2 | 3/4/7 | 5/11/18 | 0.4779 |
| T3/T4 | 16/4 | 30/6 | |
| Lymph node metastasis | |||
| N0 | 23 | 45 | 0.7354 |
| N1/N2/N3 | 5/4/2 | 18/3/4 | |
| Distant metastasis | |||
| M0 | 29 | 64 | 0.3339 |
| M1 | 5 | 6 | |
| Lymphatic duct invasion | |||
| ly0 | 12 | 22 | 0.6857 |
| ly1/ly2 | 15/7 | 40/8 | |
| Venous invasion | |||
| v0 | 26 | 58 | 0.4394 |
| v1/v2 | 7/1 | 9/3 | |
| Stage | |||
| 0/I/II | 3/9/10 | 5/24/14 | 0.7461 |
| IIIa/IIIb/IV | 4/3/5 | 15/6/6 | |
Data are presented as median (first quartile, third quartile). A, ascending colon; BMI, body mass index; C, cecum; D, descending colon; muc, mucinous carcinoma; pap, papillary adenocarcinoma; por, poorly differentiated adenocarcinoma; R, rectum; S, sigmoid colon; T, transverse colon; tub1, well-differentiated adenocarcinoma; tub2, moderately differentiated adenocarcinoma.