Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Sep 3;105(9):1135–1141. doi: 10.1111/cas.12472

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Fig 3 — Identification of the alternative polyadenylation (APA)-indicator genes in non-small cell lung cancer. (a) The APA status of the 16 genes selected in silico was confirmed in seven clinical lung cancer specimens and eight normal lung tissue specimens, and the top 10 genes were selected as the APA-indicator genes. The APA status was evaluated on the basis of the logarithm of the proportion of the full-length transcripts of the lung cancer specimens normalized to that of the normal lung tissue specimens. Results are shown as the average ± SD. The columns over the red line indicate that the proportion of the full-length transcripts of the lung cancer specimens is less than half of that of the normal lung tissue specimens. (b) The genes selected based on the results of past studies were associated with a lower frequency of 3′UTR shortening as compared to the APA-indicator genes.