. 2014 Sep 3;105(9):1135–1141. doi: 10.1111/cas.12472

Table 1.

APA score and clinicopathological characteristics

	Training set (n = 47)			Test set (n = 100)
	High APA	Low APA	P	High APA	Low APA	P
Age (years)
<70	7	19	NS	13	35	NS
≥70	10	11	NS	16	36	NS
Sex
Male	16	16	0.01	19	33	NS
Female	1	14	0.01	10	38	NS
Smoking habit
Negative history	1	12	0.03	21	38	NS
Positive history	16	18	0.03	8	33	NS
Histological type
Adenocarcinoma	11	25	NS	21	65	0.03
Others	6	5	NS	8	6	0.03
T factor
T1	4	16	NS	9	46	0.004
T2, T3	13	14	NS	20	25	0.004
N factor
N0	9	24	NS	18	66	<0.001
N1, N2	8	6	NS	11	5	<0.001
Lymphatic invasion
Negative	10	24	NS	20	61	NS
Positive	7	6	NS	9	10	NS
Vascular invasion
Negative	6	21	0.04	12	57	<0.001
Positive	11	9	0.04	17	14	<0.001
History of adjuvant chemotherapy
Negative	10	23	NS	18	59	0.04
Positive	7	7	NS	11	12	0.04

APA, alternative polyadenylation; NS, not significant.