Table 1.

Subacute Lung Injury—Required Study Criteria

1. Clinical symptoms:

a. Cough, wheezing, or dyspnea on exertion or

b. Oxygen saturation #93% on room air.

2. Abnormal pulmonary function tests:

>15% decline from pretransplantation value, plus

a. Restrictive disease: FVC <80% predicted, OR

b. Obstructive disease: FEV1 <80% with FEV1/FVC <75% predicted

3. Absence of lower respiratory tract infection

a. Negative bronchoalveolar lavage or

b. Negative transbronchial or surgical lung biopsy (if performed).