Table 1. The differentially expressed miRNAs obtained from the microarray data a .
| Up-regulated miRNAs | Down-regulated miRNAs | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| miRNA ID | Accession numberb | Mean ± SD | p-value | miRNA ID | Accession numberb | Mean ± SD | p-value | ||
| controls | patients | controls | patients | ||||||
| hsa-miR-1273c | MIMAT0015017 | 10.815±1.807 | 12.326±1.528 | 0 | hsa-miR-451a | MIMAT0001631 | 13.097±1.846 | 12.108±1.518 | 1.48E-05 |
| hsa-miR-4299 | MIMAT0016851 | 11.472±1.572 | 12.776±0.801 | 2.96E-05 | hsa-miR-16-5p | MIMAT0000069 | 14.303±1.807 | 13.610±2.370 | 0.000751 |
| hsa-miR-5739 | MIMAT0023116 | 10.619±1.356 | 11.541±2.344 | 0.000336 | hsa-miR-940 | MIMAT0004983 | 12.604±0.781 | 11.832±1.196 | 0.000914 |
| hsa-miR-6086 | MIMAT0023711 | 12.118±0.749 | 13.092±0.393 | 0.000479 | hsa-miR-574-3p | MIMAT0003239 | 13.543±1.213 | 12.967±1.083 | 0.001201 |
| hsa-miR-494 | MIMAT0002816 | 13.875±2.658 | 14.836±1.261 | 0.000687 | hsa-let-7d-5p | MIMAT0000065 | 12.501±1.392 | 11.774±1.540 | 0.001215 |
| hsa-miR-4270 | MIMAT0016900 | 14.535±0.369 | 15.402±0.295 | 0.000805 | hsa-let-7a-5p | MIMAT0000062 | 12.607±1.515 | 12.005±1.543 | 0.001448 |
| hsa-miR-642a-3p | MIMAT0020924 | 11.565±0.856 | 12.497±0.394 | 0.00081 | hsa-let-7f-5p | MIMAT0000067 | 11.268±1.840 | 10.931±1.573 | 0.001882 |
| hsa-miR-4516 | MIMAT0019053 | 12.816±2.250 | 13.213±2.188 | 0.001107 | hsa-miR-92a-3p | MIMAT0000092 | 11.667±0.915 | 11.041±1.159 | 0.003172 |
| hsa-miR-4436a | MIMAT0018952 | 10.036±0.814 | 10.981±0.136 | 0.001546 | hsa-miR-3613-3p | MIMAT0017991 | 11.611±0.516 | 11.029±0.540 | 0.004125 |
| hsa-miR-1246 | MIMAT0005898 | 11.168±1.758 | 12.040±0.808 | 0.002055 | hsa-miR-20a-5p | MIMAT0000075 | 12.332±1.069 | 11.799±0.993 | 0.004466 |
| hsa-miR-575 | MIMAT0003240 | 11.310±0.485 | 12.085±0.340 | 0.002821 | hsa-miR-1228-3p | MIMAT0005583 | 12.391±1.506 | 12.095±1.673 | 0.005944 |
| hsa-miR-4721 | MIMAT0019835 | 11.715±0.259 | 12.376±0.544 | 0.003765 | hsa-miR-3935 | MIMAT0018350 | 14.062±1.749 | 13.863±1.483 | 0.006354 |
| hsa-miR-483-5p | MIMAT0004761 | 11.676±1.349 | 12.407±0.485 | 0.004377 | hsa-miR-4700-3p | MIMAT0019797 | 11.320±0.338 | 10.762±0.225 | 0.006453 |
| hsa-miR-1249 | MIMAT0005901 | 11.148±0.327 | 11.549±1.296 | 0.004407 | hsa-miR-15b-5p | MIMAT0000417 | 11.050±1.161 | 10.733±1.234 | 0.006527 |
| hsa-miR-4443 | MIMAT0018961 | 9.865±0.774 | 10.524±0.494 | 0.004501 | hsa-miR-15a-5p | MIMAT0000068 | 11.759±1.233 | 11.300±1.294 | 0.006942 |
| hsa-miR-921 | MIMAT0004971 | 10.094±0.352 | 10.745±0.427 | 0.005608 | hsa-miR-4436b-5p | MIMAT0019940 | 11.854±0.924 | 11.438±0.585 | 0.007426 |
| hsa-miR-34b-3p | MIMAT0004676 | 10.272±1.012 | 10.779±0.696 | 0.005909 | hsa-miR-4665-5p | MIMAT0019739 | 11.620±1.406 | 11.521±1.133 | 0.007441 |
| hsa-miR-6125 | MIMAT0024598 | 13.084±2.164 | 13.256±1.945 | 0.006018 | hsa-miR-19b-3p | MIMAT0000074 | 11.257±1.140 | 10.889±1.059 | 0.008103 |
| hsa-miR-4669 | MIMAT0019749 | 11.311±0.407 | 11.954±0.842 | 0.006897 | hsa-miR-103a-3p | MIMAT0000101 | 12.390±1.097 | 11.965±1.118 | 0.009121 |
| hsa-miR-34c-3p | MIMAT0004677 | 10.318±0.923 | 10.887±0.795 | 0.007624 | hsa-miR-195-5p | MIMAT0000461 | 10.982±1.699 | 10.901±1.378 | 0.009279 |
| hsa-miR-4728-5p | MIMAT0019849 | 11.756±0.617 | 12.280±0.495 | 0.008063 | |||||
| hsa-miR-564 | MIMAT0003228 | 10.076±0.278 | 10.679±0.497 | 0.00831 | |||||
| hsa-miR-574-5p | MIMAT0004795 | 10.807±1.760 | 11.333±0.890 | 0.00873 | |||||
| hsa-miR-4788 | MIMAT0019958 | 12.324±0.978 | 12.940±0.483 | 0.009634 | |||||
a: More details are presented in S1 Table.
b: Accession numbers were obtained from miRBase database.