Table 1. Top SNPs (P<5 × 10-6) from a GWAS of adult antisocial behavior.
| SNP | CHR | POS | EFF | NEFF | AF | BETA | P |
|---|---|---|---|---|---|---|---|
| rs4728702 | 7 | 87180678 | A | T | 0.43 | −0.36 | 5.77E−07 |
| rs1016793 | 7 | 87199182 | G | A | 0.59 | 0.37 | 5.91E−07 |
| rs1128503 | 7 | 87179601 | A | G | 0.43 | −0.36 | 5.97E−07 |
| rs4728700 | 7 | 87171659 | T | C | 0.45 | −0.36 | 6.08E−07 |
| rs868755 | 7 | 87189930 | T | G | 0.41 | −0.37 | 6.15E−07 |
| rs10276036 | 7 | 87180198 | C | T | 0.43 | −0.36 | 6.22E−07 |
| rs3789244 | 7 | 87181849 | G | T | 0.43 | −0.36 | 6.22E−07 |
| rs2235026 | 7 | 87182882 | T | C | 0.43 | −0.36 | 6.32E−07 |
| rs2235021 | 7 | 87199264 | C | A | 0.57 | 0.36 | 7.15E−07 |
| rs2235020 | 7 | 87199265 | T | A | 0.57 | 0.36 | 7.30E−07 |
| rs2235046 | 7 | 87174066 | T | C | 0.45 | −0.35 | 8.20E−07 |
| rs10985923 | 9 | 126038684 | G | T | 0.93 | 0.71 | 9.10E−07 |
| rs6959435 | 7 | 87158185 | G | T | 0.43 | −0.36 | 9.82E−07 |
| rs2373586 | 7 | 87157583 | A | C | 0.43 | −0.36 | 9.85E−07 |
| rs62817660 | 7 | 87200529 | G | A | 0.57 | 0.35 | 1.03E−06 |
| rs12539098 | 7 | 87200639 | T | C | 0.57 | 0.35 | 1.04E−06 |
| rs11975994 | 7 | 87192731 | G | A | 0.43 | −0.35 | 1.05E−06 |
| rs1016794 | 7 | 87198459 | G | A | 0.57 | 0.35 | 1.05E−06 |
| rs2520464 | 7 | 87201086 | C | T | 0.57 | 0.35 | 1.06E−06 |
| rs2032582 | 7 | 87160618 | A | C | 0.45 | −0.35 | 1.23E−06 |
| rs1202167 | 7 | 87197059 | C | T | 0.57 | 0.35 | 1.37E−06 |
| rs6504898 | 17 | 52427312 | G | T | 0.56 | −0.36 | 1.42E−06 |
| rs1202168 | 7 | 87195962 | G | A | 0.57 | 0.35 | 1.53E−06 |
| rs1202169 | 7 | 87195850 | T | C | 0.57 | 0.35 | 1.55E−06 |
| rs2235013 | 7 | 87178626 | C | T | 0.51 | −0.34 | 1.83E−06 |
| rs2235033 | 7 | 87179143 | A | G | 0.51 | −0.34 | 1.83E−06 |
| rs12704364 | 7 | 87181175 | C | T | 0.51 | −0.34 | 1.83E−06 |
| rs6961665 | 7 | 87181418 | C | A | 0.51 | −0.34 | 1.83E−06 |
| rs58738000 | 2 | 11704426 | C | G | 0.92 | −0.66 | 1.87E−06 |
| rs6504902 | 17 | 52433609 | T | C | 0.56 | −0.35 | 1.88E−06 |
| rs4810138 | 20 | 57144231 | G | C | 0.33 | 0.38 | 1.90E−06 |
| rs2235027 | 7 | 87182779 | G | T | 0.51 | −0.34 | 1.91E−06 |
| rs10234411 | 7 | 87164892 | T | A | 0.45 | −0.34 | 1.94E−06 |
| rs4148738 | 7 | 87163049 | C | T | 0.45 | −0.34 | 1.96E−06 |
| rs68152859 | 2 | 11699747 | G | A | 0.92 | −0.67 | 2.02E−06 |
| rs10985911 | 9 | 126007069 | T | C | 0.93 | 0.68 | 2.04E−06 |
| rs5020877 | 2 | 11694370 | A | G | 0.92 | −0.67 | 2.12E−06 |
| rs142285425 | 9 | 125951669 | A | G | 0.93 | 0.67 | 2.34E−06 |
| rs10985900 | 9 | 125954349 | T | C | 0.93 | 0.67 | 2.34E−06 |
| rs7870519 | 9 | 125917716 | A | T | 0.93 | 0.67 | 2.34E−06 |
| rs62579000 | 9 | 125973531 | C | T | 0.93 | 0.67 | 2.34E−06 |
| rs10985892 | 9 | 125908794 | T | C | 0.93 | 0.67 | 2.35E−06 |
| rs10985908 | 9 | 125986335 | C | T | 0.93 | 0.67 | 2.35E−06 |
| rs62578996 | 9 | 125919594 | G | A | 0.93 | 0.66 | 2.56E−06 |
| rs10808072 | 7 | 87176463 | A | G | 0.51 | −0.33 | 2.69E−06 |
| rs55980995 | 5 | 121875565 | A | G | 0.88 | −0.52 | 2.84E−06 |
| rs6893509 | 5 | 121860590 | T | G | 0.89 | −0.55 | 2.92E−06 |
| rs28368138 | 9 | 21207334 | C | G | 0.95 | −0.82 | 2.97E−06 |
| rs1202165 | 7 | 87197594 | G | A | 0.59 | 0.35 | 3.00E−06 |
| rs12002466 | 9 | 125865899 | T | C | 0.93 | 0.65 | 3.40E−06 |
| rs180996880 | 2 | 11693084 | C | A | 0.92 | −0.65 | 3.41E−06 |
| rs74602468 | 5 | 121863973 | C | T | 0.90 | −0.56 | 3.48E−06 |
| rs67242082 | 6 | 94334202 | A | G | 0.86 | −0.48 | 3.66E−06 |
| rs76585835 | 5 | 121867413 | G | A | 0.90 | −0.56 | 3.83E−06 |
| rs41277128 | 9 | 125610975 | G | A | 0.93 | 0.66 | 3.85E−06 |
| rs7033878 | 9 | 125618080 | T | G | 0.93 | 0.66 | 3.88E−06 |
| rs62580884 | 9 | 125619738 | C | A | 0.93 | 0.66 | 3.88E−06 |
| rs10985798 | 9 | 125624520 | G | C | 0.93 | 0.66 | 3.88E−06 |
| rs62580922 | 9 | 125631594 | T | C | 0.93 | 0.66 | 3.88E−06 |
| rs10985807 | 9 | 125652376 | C | T | 0.93 | 0.66 | 3.88E−06 |
| rs78303085 | 9 | 125869322 | T | A | 0.93 | 0.66 | 3.96E−06 |
| rs62578960 | 9 | 125869287 | G | A | 0.93 | 0.66 | 3.97E−06 |
| rs80233205 | 5 | 121871869 | G | A | 0.90 | −0.56 | 4.03E−06 |
| rs55919124 | 5 | 121880314 | T | A | 0.90 | −0.56 | 4.05E−06 |
| rs62580923 | 9 | 125635317 | A | T | 0.93 | 0.65 | 4.13E−06 |
| rs6413435 | 19 | 18497137 | G | A | 0.83 | −0.44 | 4.18E−06 |
| rs6948766 | 7 | 87191246 | G | A | 0.52 | −0.33 | 4.32E−06 |
| rs11763872 | 7 | 87217215 | T | C | 0.49 | 0.33 | 4.40E−06 |
| rs7034822 | 9 | 125621808 | G | A | 0.93 | 0.65 | 4.46E−06 |
| rs12378760 | 9 | 125661283 | T | C | 0.93 | 0.65 | 4.46E−06 |
| rs17149293 | 5 | 121864140 | G | T | 0.90 | −0.55 | 4.53E−06 |
| rs76809806 | 5 | 121873792 | G | A | 0.90 | −0.55 | 4.66E−06 |
| rs12979706 | 19 | 18495424 | G | A | 0.83 | −0.44 | 4.75E−06 |
| rs12514901 | 5 | 121878119 | T | G | 0.89 | −0.54 | 4.84E−06 |
| rs78479583 | 5 | 121871427 | G | A | 0.90 | −0.55 | 4.96E−06 |
Abbreviations: AF, allele frequency of the effect allele; BETA, regression coefficient; CHR, chromosome; EFF, effect allele; GWAS, genome-wide association study; NEFF, non-effect allele; POS, position (in base pairs); SNP, single-nucleotide polymorphism.