Table 2. Top genes associated with adult antisocial behavior.
| Gene name | Chromosome | Gene P-value | Gene q-value | Brain exp |
|---|---|---|---|---|
| ABCB1 | 7 | 1.42E−06 | 0.033 | 210 |
| CD46 | 1 | 1.28E−05 | 0.297 | 451 |
| ABCB5 | 7 | 2.06E−05 | 0.476 | — |
| IFNA7 | 9 | 2.34E−05 | 0.542 | — |
| MIR600 | 9 | 2.53E−05 | 0.584 | NA |
| MIR600HG | 9 | 2.53E−05 | 0.584 | NA |
| STRBP | 9 | 3.55E−05 | 0.821 | 359 |
| GREB1 | 2 | 3.85E−05 | 0.891 | 163 |
| RC3H2 | 9 | 3.88E−05 | 0.897 | 498 |
| ZBTB6 | 9 | 4.28E−05 | 0.989 | 190 |
| IFNA17 | 9 | 4.55E−05 | 1.000 | — |
| RABGAP1 | 9 | 7.97E−05 | 1.000 | 1228 |
| NKAIN3 | 8 | 8.04E−05 | 1.000 | 281 |
| OLIG2 | 21 | 8.11E−05 | 1.000 | 155 |
| ZBTB26 | 9 | 8.24E−05 | 1.000 | 153 |
| IFNA16 | 9 | 8.52E−05 | 1.000 | — |
| IFNA10 | 9 | 9.68E−05 | 1.000 | — |
Brain exp. is the maximum of average expression for nine brain regions; ‘—' is below background; NA indicates measurement not available because the gene was not present on array.
Notes: Gene P-value and gene q-value refer to the uncorrected P-values and the q-values based on a Benjamini and Hochberg false discovery rate for the gene-based tests. A gene was presumed to be expressed in the brain if the maximum expression level across the nine regions was higher than 16.0 because this is above the background signal for the arrays. Expression ranges from 5–20,140; median=108; 90th percentile=484. For comparison, the neurotransmitter receptor gene HTR1B (serotonin 1D beta receptor) that is normally expressed in the brain has a maximum expression of 182.