Table 2. Correlation of age with white matter measures and in patients with schizophrenia (SZ) and normal controls (NC) separately.
White matter measures |
SZ |
NC |
||
---|---|---|---|---|
r | P | r | P | |
Left frontal FA | −0.55 | 0.001a | −0.41 | 0.012 |
Whole-brain FA | −0.71 | <0.001a | −0.36 | 0.030 |
Left frontal glutamate | −0.44 | 0.010 | −0.37 | 0.027 |
Left frontal NAA | −0.63 | <0.001a | −0.36 | 0.032 |
Left frontal myo-inositol | 0.40 | 0.021 | 0.23 | 0.18 |
Left frontal choline | 0.05 | 0.79 | 0.09 | 0.59 |
Abbreviations: FA, fractional anisotropy of white matter; NAA, N-acetylaspartate.
Nominally (P<0.05) significant correlations that were replicated across groups are in bold.
Significant after Bonferroni correction for 12 comparisons (P<0.004).