TABLE 1 .
Top 25 K. pneumoniae KPPR1 lung fitness genesa
| Locus ID (VK055_x) | Gene | Product | Ratio (input/lung) |
|---|---|---|---|
| 5014 | Capsule assembly Wzi family protein | 2820.95 | |
| 3141 | rfaH | Transcriptional activator | 2696.77 |
| 5096 | Hypothetical protein | 2486.08 | |
| 3202 | ilvC | Ketol-acid reductoisomerase | 2248.61 |
| 3832 | argR | Arginine repressor | 1140.74 |
| 5025 | Undecaprenyl-phosphate glucose phosphotransferase | 840.55 | |
| 5012 | galF | Regulatory protein | 704.99 |
| 3206 | ilvE | Branched-chain amino acid aminotransferase | 581.10 |
| 3515 | Rhodanese-like domain protein | 508.09 | |
| 4417 | MarR family protein | 442.14 | |
| 4811 | purF | Amidophosphoribosyltransferase | 378.16 |
| 4619 | purL | Phosphoribosylformylglycinamidine synthase | 312.03 |
| 1194 | trpD | Anthranilate synthase component II | 301.31 |
| 4135 | serA | d-3-Phosphoglycerate dehydrogenase; provisional | 248.61 |
| 2495 | leuC | 3-Isopropylmalate isomerase subunit, dehydratase component | 246.77 |
| 3142 | tatC | Twin arginine-targeting protein translocase | 219.96 |
| 3205 | ilvD | Dihydroxy acid dehydratase | 203.61 |
| 5023 | Hypothetical protein | 172.11 | |
| 4883 | rcsB | Transcriptional regulator | 126.39 |
| 2215 | phoR | Phosphate regulon sensor kinase | 110.92 |
| 4579 | pheA | Bifunctional chorismate mutase/prephenate dehydratase | 94.55 |
| 3368 | 2-Oxo-3-deoxygalactonate 6-phosphate aldolase | 90.01 | |
| 2084 | copA | Copper-translocating P-type ATPase | 69.70 |
| 3086 | purH | Phosphoribosylaminoimidazole carboxamide formyltransferase | 66.84 |
| 3791 | aroE | Dehydroshikimate reductase | 61.93 |
a
Experimentally validated genes are shown in boldface.