TABLE 4 .
Independent parameters associated with mycological failure at week 2 for 123 patients
| Parameter | Univariate analysis |
Multivariate analysisa |
|||
|---|---|---|---|---|---|
| % with mycological failure (no./total) | % with mycological cure (no./total) | P value | OR (95% CI) | P | |
| Male sex | 92.2 (47/51) | 77.8 (56/72) | 0.046 | ||
| Disseminated infection | 74.5 (38/51) | 59.7 (43/72) | 0.122 | ||
| Mixed infections | 21.6 (11/51) | 8.3 (6/72) | 0.061 | 5.6 (1.4–22.6) | 0.015 |
| Lack of 5FC | 54.9 (28/51) | 34.7 (25/72) | 0.029 | 5.8 (2.0–17.2) | 0.001 |
| Infection by AD hybrid | 7.8 (4/51) | 31.9 (23/72) | 0.002 | 0.1 (0.02–0.46) | 0.003 |
| Serum antigen titer > 512 | 63.8 (30/47) | 40.9 (27/66) | 0.022 | 5.0 (1.7–14.4) | 0.003 |
a
OR, odds ratio; CI, confidence interval.