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. 2014 Jul 11;70(5):533–544. doi: 10.1093/gerona/glu090

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© The Author 2014. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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Figure 7. — Terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling-positive staining (A) is visualized by immunofluorescence staining (×40) in left ventricle (LV) samples of young adult wild-type (YWT), old WT (OWT), and old Sod2 Tg (OTg), and DNA fragmentation (B) was used as a marker of apoptosis through quantification of mononucleosomes and oligonucleosomes via ELISA in LV samples of YWT, young adult Sod2 Tg (YTg), OWT, and OTg. Data are expressed as means ± standard error of the mean. “a” indicates a significant difference vs YWT (p < .05). “b” indicates a significant difference vs YTg (p < .05).