Table 4.
Magnetic Resonance Imaging Characteristics Associated With Herpes Simplex Encephalitis in Multivariate Logistic Regression, Final Modelsa
| Characteristic | Model 1: HSE Compared With All Non-HSE Cases (n = 209) |
Model 2: HSE Compared With Other Infectious Cases (n = 90) |
Model 3: HSE Compared With Autoimmune Cases (n = 75) |
|||
|---|---|---|---|---|---|---|
| OR (95% CI) (Total No. With MRI Characteristic) | P Value | OR (95% CI) (Total Number With MRI Characteristic) | P Value | OR (95% CI) (Total No. With MRI Characteristic) | P Value | |
| Bilateral TL | 0.38 (.18–.79) (n = 82) | .010 | 0.30 (.11–.82) (n = 31) | .019 | 0.24 (.06–.94) (n = 22) | .040 |
| Lesions outside of TL, cingulate, or insula | 0.37 (.18–.74) (n = 106) | .005 | 0.41 (.16–1.05) (n = 39) | .064 | 0.36 (.10–1.35) (n = 29) | .13 |
| Restricted diffusion | 1.62 (.75–3.50) (n = 50) | .22 | 0.67 (.24–1.85) (n = 29) | .44 | 0.81 (.17–3.85) (n = 21) | .79 |
| Hemorrhage | 1.51 (.44–5.13) (n = 15) | .51 | … | … | 8.95 (.23–348.65) (n = 7) | .24 |
| Enhancement | 0.98 (.49–1.94) (n = 86) | .95 | 0.56 (.21–1.52) (n = 41) | .26 | 0.47 (.12–1.81) (n = 32) | .27 |
Abbreviations: CI, confidence interval; HSE, herpes simplex encephalitis; MRI, magnetic resonance imaging; OR, odds ratio; TL, temporal lobe.
a Adjusted for age, sex, and all variables listed in the table.