Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jun 11;5:11289. doi: 10.1038/srep11289

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) The distinct conformations of G loop at 0 ns (blue), 2 ns (silver), 3 ns (yellow), and 6 ns (red) during the Targeted MD simulation. (b) and (c) show the time course of the interaction between G-loop (blue) and CD-loop (yellow) through intrasubunit E303-H221 (b) and intersubunit R312–H221 (c). (d) and (e) show the time course of interactions between N-terminus (purple) and CD-loop (yellow) through C54–K219 (d) and G52/H53/C54-H221 (e). (f–h) show the strengthened interactions between CD-loop (yellow) and C-linker (red) through H221–R189 (f), between C-linker (red) and G-loop (blue) through P186–E303 (g) and between adjacent G-loops through E303–R312 (h).