TABLE 4.
Estimates of sensitivity and specificity for HSV-2 assays grouped by city and by HIV status
Sensitivity or specificity and assay | % Sensitivity or specificity in:
|
% Samples
|
|||
---|---|---|---|---|---|
Yaoundé | Kisumu | Ndola | HIV− | HIV+ | |
Sensitivity | |||||
MAb EIA | 97 | 98 | 100 | 95 | 100 |
Gull Premier test | 90 | 85 | 83 | 77 | 92 |
Kalon Biological | 92 | 94 | 89 | 89 | 94 |
Biokit | 89 | 89 | 77 | 83 | 89 |
Radim | 81 | 87 | 78 | 74 | 92 |
Euroimmun | 97 | 95 | 95 | 92 | 98 |
IBL | 97 | 98 | 68 | 90 | 96 |
HerpeSelect | 100 | 100 | 100 | 100 | 100 |
DiaSorin | 99 | 94 | 92 | 96 | 94 |
Captia HSV-2 Type- Specific IgG | 100 | 93 | 100 | 99 | 94 |
Specificity | |||||
MAb EIA | 98 | 98 | 94 | 98 | 88 |
Gull Premier test | 98 | 95 | 100 | 99 | 88 |
Kalon Biological | 98 | 95 | 100 | 99 | 88 |
Biokit | 90 | 92 | 97 | 95 | 81 |
Radim | 100 | 98 | 100 | 99 | 100 |
Euroimmun | 88 | 77 | 100 | 88 | 89 |
IBL | 83 | 50 | 100 | 76 | 100 |
HerpeSelect | 72 | 57 | 93 | 74 | 71 |
DiaSorin | 68 | 41 | 67 | 65 | 19 |
Captia HSV-2 Type- Specific IgG | 58 | 30 | 51 | 53 | 0 |