Table 1.
The Sensitivity and Specificity of the Xpert MTB/RIF, MGIT, 2% Ogawa Culture, and Smear Analyses for Detection of MTB in Fecal Specimens From TB and Non-TB Patients
| Test | Test Result | TB (n = 56) | Non-TB (n = 37) | Sensitivity | 95% CI | Specificity | 95%CI |
|---|---|---|---|---|---|---|---|
| Xpert MTB/RIF | Positive | ||||||
| Sputum Smear Result | |||||||
| Negative (n = 8) | 4 | 0 | 50.0 | 15.7–84.3 | 100a | 86.2–100a | |
| ± (n = 21) | 17 | 0 | 81.0 | 58.1–94.6 | |||
| 1–3+ (n = 27) | 27 | 0 | 100 | 81.7–100 | |||
| Negative | 8 | 37 | 85.7a | 73.8–93.6a | |||
| MGIT | Positive | 15 | 0 | 31.9 | 19.1–47.1 | 100 | 82.8–100 |
| Negative (MAC) | 32 | 29 (4) | |||||
| Contamination | 9 | 4 | |||||
| 2% Ogawa culture | Positive | 12 | 0 | 21.4 | 11.6–34.4 | 100 | 86.2–100 |
| Negative (MAC) | 44 | 33 (4) | |||||
| Contamination | 0 | 0 | |||||
| Smearb | Positive | 26 | 2 | 47.3 | 33.7–61.2 | 94.6 | 81.8–99.3 |
| Negative | 29 | 35 | |||||
Abbreviations: CI, confidence interval; MAC, Mycobacterium avium complex; MGIT, mycobacterial growth indicator tubes; MTB, Mycobacterium tuberculosis; TB, tuberculosis.
a Total sensitivity and sensitivity of the Xpert MTB/RIF test using fecal specimens.
b The fecal smear analysis was not performed on one of the samples.