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. 2015 May 25;62(2):142–151. doi: 10.1002/jmrs.108

Table 3.

Summary of dosimetric results for SBRT planning study comparing 3DCRT versus IMRT versus VMAT–RA for the treatment of abdominal metastasis

Reference Bignardi et al.11 Kumar et al.12
Target area Lymph nodes (abdominal region) 45 Gy/6Fx Locally advanced pancreatic cancer
Dose/Fx Plans acceptable if PTV dose >36 Gy (spinal cord 53 ± 21 cm3) (small bowel 780 ± 633 cm3) 25 Gy/1Fx
Variable 3DCRT IMRT (co-planar) VMAT RA DS VMAT DS IMRT
Patients 14 15
Effective treatment time (min) 6.3 ± 0.5 10.6 ± 1.2 3.7 ± 0.4 9 11.45
PTV: mean volume (cm3) 44.0 ± 0.4 44.26 ± 0.4 44.5 ± 0.3 135 135
PTV V95 (%) 82.5 ± 9.6 84.5 ± 8.2 90.2 ± 5.2 97.5 98.6
Healthy tissue V10Gy (%) 6.3 ± 4.4 4.0 ± 1.9 3.1 ± 1.81 NA NA
Healthy tissue integral dose (Gy cm3 10−5) NA NA NA 0.37 0.35
Healthy tissue CI60% 3.8 ± 1.49 3.2 ± 0.7 2.5 ± 0.3 NA NA
Left kidney V5 Gy (%) NA NA NA 7.6 17.6
Small bowel D1% (Gy) or D1cc (Gy) D1% (Gy) 23.02 ± 10.81 D1% (Gy) 19.01 ± 11.50 D1% (Gy) 18.01 ± 10.83 D1cc (Gy) 24.7 D1cc (Gy) 25.6
Small bowel V36Gy or V20 Gy (%) V36Gy 0.3 ± 0.7 V36Gy 0.2 ± 0.4 V36Gy 0.1 ± 0.2 V20 Gy 18.8 V20 Gy 21.9
Spinal cord Dmax (Gy) 13.7 ± 5.7 13.9 ± 3.2 9.6 ± 2.3 11.6 11.7
Spinal cord D1% (Gy) or V5 (Gy) D1% (Gy) 12.9 ± 5.9 D1% (Gy) 10 ± 2.8 D1% (Gy) 7.8 ± 2.3 V5 (Gy) 22.2 V5 (Gy) 23.8
Liver mean (Gy) 4.3 ± 4.3 3.8 ± 4.0 3.6 ± 3.9 2.8 2.5
MUs 1554 ± 153 2583 ± 699 2186 ± 211 5437 6894

MU, monitor units; PTV, planning target volume; IMRT, intensity modulated radiotherapy; VMAT, volumetric modulated arc therapy; 3DCRT, 3D conformal radiotherapy therapy; RA, rapid arc; Dmax, maximum dose; SD, standard deviation; CI, conformity index; Fx, fraction; DS, dose sparing; Vn, volume of tissue receiving n dose (Gy); NA, not applicable; Dxx%, dose (Gy) to xx% of volume.