TABLE 2. Plasma Interleukin-6 Concentrations Between Baseline and 24 and 48 hours by Treatment Group Among Patients With Abdominal Injury or Intra-abdominal Sepsis.

Patient Type	Treatment Group	Baseline (pg/mL)	24 hr (pg/mL)	P Value for Difference at 24 hr Between Groups*	48 hr (pg/mL)	P Value for Difference at 48 hr Between Groups*
Abdominal injury patients	ABThera	679.0 (210.1–2935.96)	573.4 (352.3–827.8)	0.51	288.8 (177.6–461.6)	>0.99
	Barker's vacuum pack	1854.1 (771.9–2982.1)	430.0 (194.4–756.1)		747.6 (212.6–797.0)
Intra-abdominal sepsis patients	ABThera	553.9 (102.8–3123.8)	315.5 (152.3–678.6)	0.66	200.1 (51.6–339.7)	0.89
	Barker's vacuum pack	3518.0 (2254.4–5488.7)	1430.8 (680.3–4938.5)		813.0 (172.6–3387.5)

Values in Table summarizing plasma cytokine concentrations represent medians (with associated interquartile ranges). Tests of hypotheses and P values were estimated using mixed-effects regression models.

*Test of hypothesis comparing whether peritoneal fluid or plasma cytokine concentrations are significantly different at 24 or 48 hr versus baseline between patients randomized to the ABThera versus Barker's vacuum pack.