TABLE 3. Prespecified Secondary Efficacy and Safety Outcomes by Treatment Group.

	Median (IQR)
Variable	ABThera (n = 23)	Barker's Vacuum Pack (n = 22)	P
Efficacy outcomes
Number of days alive and without the following condition or treatment within the first 30 d
Open abdomen	27 (0–28)	18 (0–28)	0.08
Mechanical ventilation	18 (12–25)	12 (0–26)	0.12
Renal replacement therapy	30 (19–30)	24 (1–30)	0.05
ICU stay	17 (11–23)	9 (0–23)	0.10
Hospital stay	0 (0–6)	0 (0–11)	0.43
Safety outcomes
Enterocutaneous or enteroatmospheric fistula, n (%)	2 (8.7)	1 (4.6)	0.52
Intra-abdominal pressure, mm Hg, median (IQR)
0–24 hr (n = 33)	16 (11–19)	14 (11–17)
24–48 hr (n = 35)	16 (12–19)	16 (12–18)
48–72 hr (n = 8)	15 (11–21)	19 (18–20)
Grade III/IV intra-abdominal hypertension, n (%)*
0–24 hr	1/20 (5.0)	0/13 (0)	>0.99
24–48 hr	2/19 (10.5)	1/16 (6.7)	>0.99
48–72 hr	1/3 (33.3)	1/5 (20.0)	>0.99
Recurrent abdominal compartment syndrome, n (%)†	0 (0)	0 (0)	NA

*Defined as a mean daily value of intra-abdominal pressure of 21 mm Hg or more.

†Defined as an intra-abdominal pressure of more than 20 mm Hg with new onset organ failure in a patient with an open abdominal wound.

NA indicates not applicable.