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. 2013 Dec 21;3(4):304–307. doi: 10.5588/pha.13.0049

TABLE 3.

Proportion of culture-negative results by smear grading at treatment follow-up among TB patients enrolled in clinical trials at NIRT, India, 2000–2012

Smear grade* Culture-negative results/cultures performed
Month 1 n/N (%) Month 2 n/N (%) Month 3 n/N (%) Month 4 n/N (%) Month 5 n/N (%) Month 6 n/N (%)
1+ 149/563 (27) 252/333 (76) 145/184 (79) 89/122 (73) 43/65 (66) 40/67 (60)
2+ 4/57 (7) 10/20 (50) 5/14 (36) 2/9 (22) 2/11 (18) 1/6 (17)
3+ 1/5 (20) 0/1 (0) 0/3 (0) 0/2 (0) 0/1 (0) 0/0 (0)
*

1+: <6 bacilli/high power field (HPF); 2+: 6–100 bacilli/HPF; 3+: >100 bacilli/HPF or large clumps.

TB = tuberculosis; NIRT = National Institute for Research in Tuberculosis.